Selective TnsC recruitment enhances the fidelity of RNA-guided transposition | Nature
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Sanne Klompe on Twitter: "@Audebe Finally, we identified sequence patterns of the transposon ends that dictate CAST compatibility groups. We present a set of five highly active, high fidelity, and orthogonal systems
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Sanne Klompe on Twitter: "We showed that integration efficiency is cargo-size dependent but can facilitate payloads of >10kb in size. 3/8" / Twitter
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Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons - ScienceDirect
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases | Nature Biotechnology
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Sanne Klompe on Twitter: "This year was a blast! From empty benches to a fully running lab, and now our first paper! Super gratefull to my amazing mentor @shsternberg and talented labmates Leo and Tyler. Can't wait for what comes next! 7/8 https://t.co ...
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Structures of the holo CRISPR RNA-guided transposon integration complex | Nature